The VicinitySampler is a generator of constitutional isomers. It needs to be
provided with a starting constitution and it makes random moves in
constitutional space from there. This generator was first suggested by
Faulon [Faulon, J. L., Stochastic generator of chemical structure .2. Using simulated
annealing to search the space of constitutional isomers, Journal of Chemical Information and Computer
Sciences, 1996, 36:731-740].